Hydrocortisone And Iodoquinol

FDA Drug Information • Also known as: Hydrocortisone Iodoquinol

Brand Names
Hydrocortisone Iodoquinol
Drug Class
Corticosteroid [EPC]
Route
TOPICAL
Dosage Form
CREAM
Product Type
HUMAN PRESCRIPTION DRUG

Description

DESCRIPTION Each gram contains 10 mg of hydrocortisone and 10 mg of iodoquinol in a vehicle consisting of: cetyl alcohol, glycerin, glyceryl stearate SE, mineral oil, PEG-100 stearate, phenoxyethanol, purified water, stearyl alcohol, white petrolatum, xanthan gum. Paraben Free. Chemically, hydrocortisone is [Pregn-4-ene-3, 20-dione, 11, 17, 21-trihydroxy-, (11β)-] with the molecular formula C 21 H 30 O 5 ) and is represented by the following structural formula: and iodoquinol, 5, 7-diiodo-8-quinolinol (C 9 H 5 I 2 NO) is represented by the following structural formula: Hydrocortisone is an anti-inflammatory and antipruritic agent, while iodoquinol is an antifungal and antibacterial agent. Chemical Structure Chemical Structure

What Is Hydrocortisone And Iodoquinol Used For?

INDICATIONS Based on a review of a related drug by the National Research Council and subsequent FDA classification for that drug, the indications are as follows: "Possibly" Effective: Contact or atopic dermatitis; impetiginized eczema; nummular eczema; endogenous chronic infectious dermatitis; stasis dermatitis; pyoderma; nuchal eczema and chronic eczematoid otitis externa; acne urticata; localized or disseminated neurodermatitis; lichen simplex chronicus; anogenital pruritus (vulvae, scroti, ani); folliculitis; bacterial dermatoses; mycotic dermatoses such as tinea (capitis, cruris, corporis, pedis); moniliasis; intertrigo. Final classification of the less-than-effective indications requires further investigation.

Dosage and Administration

DOSAGE AND ADMINISTRATION Apply to affected area 3 to 4 times daily in accordance with physician's directions.

Side Effects (Adverse Reactions)

ADVERSE REACTIONS The following local adverse reactions are reported infrequently with topical corticosteroids. These reactions are listed in an approximate decreasing order of occurrence: burning, itching, irritation, dryness, folliculitis, hypertrichosis, acneiform eruptions, hypopigmentation, perioral dermatitis, allergic contact dermatitis, maceration of the skin, secondary infections, skin atrophy, striae and miliaria.

Warnings and Precautions

WARNING FOR EXTERNAL USE ONLY.

Contraindications

CONTRAINDICATIONS This product is contraindicated in persons with known or suspected hypersensitivity to any of the ingredients of the product.

Pregnancy and Breastfeeding

Pregnancy Category C Animal reproduction studies have not been conducted with this product. It is also not known whether this product can affect reproduction capacity or cause fetal harm when administered to a pregnant woman. This product should be used by a pregnant woman only if clearly needed or when potential benefits outweigh potential hazards to the fetus.

Nursing Mothers It is not known whether this drug is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when this product is administered to a nursing woman.

How Supplied

HOW SUPPLIED 1 oz. tubes, NDC 69367-286-01 To report a serious adverse event or obtain product information, call 1-844-221-7294.

About This Information

This drug information is sourced from FDA-approved labeling via the openFDA database. It is intended for educational and reference purposes only. This is not medical advice. Always consult your healthcare provider before making decisions about medication. Drug information may be updated by the FDA; check with your pharmacist for the most current information.

What are side effects?

Side effects are unwanted reactions that can occur when taking a medication. They range from mild (headache, nausea) to severe (allergic reactions, organ damage). Not everyone experiences side effects, and severity varies. Report any concerning side effects to your doctor.

What are drug interactions?

Drug interactions occur when a medication is affected by another drug, food, or supplement. Interactions can make medications less effective or cause dangerous side effects. Always tell your doctor about all medications and supplements you take.