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Acetaminophen, Dextromethorphan Hydrobromide, Guaifenesin, Phenylephrine Hydrochloride

FDA Drug Information • Also known as: Alka-Seltzer Plus Maximum Strength Cough, Mucus And Congestion Powermax, Alka-Seltzer Plus Severe...

Brand Names
Alka-Seltzer Plus Maximum Strength Cough, Mucus And Congestion Powermax, Alka-Seltzer Plus Severe Sinus Cold And Cough Liquid Gels, Basic Care Daytime Severe Cold And Flu, Basic Care Tussin Cf Severe, Childrens Tukol Multi-Symptom Cold And Flu, Cold And Flu Relief, Cold Flu And Sore Throat Relief, Cold, Flu And Sore Throat Maxium Strength, Cooling Severe Daytime, Cvs Severe Multi-Symptom Cough Cold Flu, Daytime Cold Flu, Daytime Severe, Daytime Severe Cold And Flu, Daytime Severe Cold And Flu Relief, Daytime Severe Cold And Flu Relief Softgels, Dg Health Cold And Flu Severe, Dg Health Day Time Severe Cold And Flu Relief, Dg Health Tussin, Dolomax Cold Cough, Equate Cold And Flu, Equate Daytime Cold And Flu, Equate Maximum Strength Daytime Severe Cold And Flu Softgels, Equate Vapor Ice Cold And Flu, Foster And Thrive Daytime Severe Cold And Flu Relief, Good Sense Day Time Cold And Flu, Good Sense Severe Day Time Cold And Flu, Leader Daytime Severe Cold And Flu Relief, Leader Tussin Cf, Maximum Strength Cold, Flu And Sore Throat, Maximum Strength Mucinex Fast-Max Cold And Flu, Maximum Strength Non Drowsy Daytime Severe Cold And Flu, Medi-First Cough Cold, Medi-First Plus Cough Cold, Medique At Home Decorel Forte, Medique Decorel Forte, Meijer Adult Severe Multi-Symptom Cough Cold Flu, Physicians Care Non-Drowsy Cold And Cough, Quality Choice Daytime Severe Cold And Flu, Quality Choice Maximum Strength Daytime Cold And Flu, Right Remedies Daytime Severe Cold And Flu Softgel, Robitussin Severe Multi-Symptom Cough Cold Flu, Severe Cold And Flu, Severe Cold And Flu Relief, Severe Cold And Flu Relief Daytime, Severe Sinus Congestion Relief, Severe Tussin Cf, Topcare Day Time Cold And Flu, Topcare Day Time Severe Cold And Flu, Topcare Tussin Cf Max, Tussin Severe, Tussin Severe Cough Cold Flu, Tylenol Cold Flu Severe, Tylenol Cold Plus Flu Severe, Tylenol Cold Plus Flu Severe Severe, Up And Up Daytime Honey Cold Flu, Walgreen Severe Multi-Symptom Cough Cold Flu
Drug Class
Expectorant [EPC]
Route
ORAL
Dosage Form
SOLUTION
Product Type
HUMAN OTC DRUG

What Is Acetaminophen, Dextromethorphan Hydrobromide, Guaifenesin, Phenylephrine Hydrochloride Used For?

Uses

  • temporarily relieves these symptoms occurring with a cold or flu:
  • cough due to minor throat and bronchial irritation
  • nasal congestion
  • sinus congestion and pressure
  • minor aches and pains
  • sore throat
  • headache
  • temporarily reduces fever
  • helps loosen phlegm (mucus) and thin bronchial secretions to drain bronchial tubes and make coughs more productive

    • Dosage and Administration

    Directions

  • do not take more than 5 doses in any 24-hour period
  • do not exceed recommended dosage. Taking more than the recommended dose (overdose) may cause serious liver damage.
  • measure only with dosing cup provided
  • keep dosing cup with product
  • mL = milliliter
  • this adult product is not intended for use in children under 12 years of age age dose adults and children 12 years and over 20 mL every 4 hours children under 12 years do not use

    • Warnings and Precautions

    Warnings Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take

  • more than 4,000 mg of acetaminophen in 24 hours
  • with other drugs containing acetaminophen
  • 3 or more alcoholic drinks every day while using this product Allergy alert: Acetaminophen may cause severe skin reactions. Symptoms may include:
  • skin reddening
  • blisters
  • rash If a skin reaction occurs, stop use and seek medical help right away. Sore throat warning: If sore throat is severe, persists for more than 2 days, is accompanied or followed by fever, headache, rash, nausea, or vomiting, consult a doctor promptly. Do not use
  • if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson’s disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product.
  • with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist.
  • if you have ever had an allergic reaction to this product or any of its ingredients Ask a doctor before use if you have
  • liver disease
  • heart disease
  • high blood pressure
  • thyroid disease
  • diabetes
  • trouble urinating due to an enlarged prostate gland
  • cough that occurs with too much phlegm (mucus)
  • persistent or chronic cough such as occurs with smoking, asthma, chronic bronchitis, or emphysema Ask a doctor or pharmacist before use if you are taking the blood thinning drug warfarin When using this product do not use more than directed Stop use and ask a doctor if
  • you get nervous, dizzy or sleepless
  • pain, cough, or nasal congestion gets worse or lasts more than 7 days
  • fever gets worse or lasts more than 3 days
  • redness or swelling is present
  • new symptoms occur
  • cough comes back or occurs with rash or headache that lasts. These could be signs of a serious condition. If pregnant or breast-feeding, ask a health professional before use. Keep out of reach of children. Overdose warning: In case of overdose, get medical help or contact a Poison Control Center right away (1-800-222-1222). Prompt medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.

    • About This Information

    This drug information is sourced from FDA-approved labeling via the openFDA database. It is intended for educational and reference purposes only. This is not medical advice. Always consult your healthcare provider before making decisions about medication. Drug information may be updated by the FDA; check with your pharmacist for the most current information.

    What are side effects?

    Side effects are unwanted reactions that can occur when taking a medication. They range from mild (headache, nausea) to severe (allergic reactions, organ damage). Not everyone experiences side effects, and severity varies. Report any concerning side effects to your doctor.

    What are drug interactions?

    Drug interactions occur when a medication is affected by another drug, food, or supplement. Interactions can make medications less effective or cause dangerous side effects. Always tell your doctor about all medications and supplements you take.